Dietary Protein-Induced Proctisis and Proctolisis
Proctitis is an inflammation of the lining of the rectum called the rectal
mucosa. A continuous sensation or urge related to bowel movements is the most common symptom of
proctitis which can be accompanied by
constipation, pain or mucus and blood.
These diseases typically occur in the
first few months of life, with blood-streaked stools in otherwise healthy-looking infants. The majority of cases are seen in the breast- fed infants, with the remainder in infants fed with cow's milk or soy
protein-based formula. The mechanism underlying the disorder is unknown but it is not associated with raised
IgE antibody levels.
Diagnosis is obtained through a response to
dietary elimination of the causal food protein. For breast-fed infants, maternal restriction of cow's milk (and more rarely other foods such as soy or egg) is required.
If maternal elimination diet fails,
some children need to feed off of an amino acid formula to help be rid of the associated symptoms. Most patients are believed to outgrow their
hypersensitivity in 1 year.
Treatment of gastrointestinal symptoms…