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Dietary Protein-Induced Proctisis and Proctolisis


Proctitis is an inflammation of the lining of the rectum called the rectal mucosa. A continuous sensation or urge related to bowel movements is the most common symptom of proctitis which can be accompanied by constipation, pain or mucus and blood.

These diseases typically occur in the first few months of life, with blood-streaked stools in otherwise healthy-looking infants. The majority of cases are seen in the breast- fed infants, with the remainder in infants fed with cow's milk or soy protein-based formula. The mechanism underlying the disorder is unknown but it is not associated with raised IgE antibody levels.

Diagnosis is obtained through a response to dietary elimination of the causal food protein. For breast-fed infants, maternal restriction of cow's milk (and more rarely other foods such as soy or egg) is required.

If maternal elimination diet fails, some children need to feed off of an amino acid formula to help be rid of the associated symptoms. Most patients are believed to outgrow their hypersensitivity in 1 year.

Treatment of gastrointestinal symptoms…


by AAA Editorial Board
Date of publication: 01/02/2006
Last update: 26/01/2009
 

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